Sir Tim Berners-Lee is the inventor of the World Wide Web, the HTML markup language, the URL system, and HTTP. He is a key figure in computer science and has received numerous accolades including the Turing Award.
This is based on winning 3 head-to-head matchups with other famous people, but also losing 20 head-to-head matchups.
Most recently Tim Berners-Lee lost a matchup to Frank Gehry (#1217) voted by someone from Canada.