Drew Brees is a renowned American football quarterback who played 20 seasons in the NFL, primarily with the New Orleans Saints. He is celebrated for leading the Saints to their first Super Bowl win and setting multiple NFL records.
This is based on winning 10 head-to-head matchups with other famous people, but also losing 63 head-to-head matchups.
Most recently Drew Brees lost a matchup to Seth MacFarlane (#145) voted by someone from United Kingdom.